Crosstalk on the atrial channel

Tracing
N° 17
Manufacturer Medtronic Device PM Field Refractory periods, PMT
Patient

74-year-old man implanted with an Ensura DR dual-chamber pacemaker for complete atrioventricular block after aortic valve surgery; atrial lead positioned on the right atrium, ventricular lead positioned on the upper septum; asymptomatic patient, control visit 3 months after implantation.

Graph and trace

Tracing 17a: tracing recorded at patient arrival; programming in DDDR mode; the first line corresponds to lead I on which the markers are superimposed, the second line corresponds to the atrial EGM, the third line to lead II and the last line to lead III;

  1. AP-VP-AR sequences with fixed VP-AR intervals; atrial pacing appears to be effective; the atrial EGM shows the atrial depolarization events according to the different APs confirming an effective atrial capture; effective ventricular capture; following each VP, the atrial EGM shows a small signal probably corresponding to ventricular crosstalk on the atrial channel;

Tracing 17b: change in programming with prolongation of the post-ventricular atrial blanking;

  1. same tracing and programming as above;
  2. change in programming with prolongation of the blanking (programming of partial blanking);
  3. the atrial signal sensed after each ventricular pacing is identical but is now sensed during the post-ventricular atrial blanking period (fixed VP-Ab intervals);

Tracing 17c: modification in programming (partial blanking to partial plus);

  1. same tracing and programming as above;
  2. change in programming (partial blanking plus);
  3. disappearance of crosstalk.
Comments

Post-ventricular atrial blanking is the first component of the post-ventricular atrial refractory period. Traditionally, no sensing was possible in a window identified as a blanking which constituted an absolute refractory period. On the new pacemaker platforms, this differentiation between blanking (absence of sensing and absence of visualization of the signal on the chain of markers) and refractory periods (sensing possible with visualization on the chain of markers) is less clear-cut. Indeed, according to the programming, an atrial event sensed during post-ventricular atrial "blanking" can be visualized on the chain of markers and interfere with the functioning of different algorithms. There are 3 programming options:

  1. if the PVAB method is programmed to "absolute", the functioning is identical to the older pacemakers and the event does not appear on the marker chain;
  2. if the PVAB method is programmed to "partial", it should be noted that the first 30 milliseconds correspond to an absolute blanking so as to avoid recording of the pacing spike; an atrial event occurring in the period after these 30 ms appears on the marker chain and is labeled Ab; this atrial event does not trigger an AV delay but is counted for atrial arrhythmia diagnostic purposes; atrial sensitivity is not altered;
  3. if the PVAB method is programmed to "partial +", the functioning is identical to the previous setting except that after a sensed or paced ventricular event, the sensitivity is temporarily decreased to reduce the risk of crosstalk.

A signal detected in the PVAB (classified as Ab) likewise to a signal detected in the PVARP (classified as AR) does not trigger an AV delay but is counted for the diagnosis of atrial arrhythmias.

In this patient, the diagnosis of crosstalk is evident. The sensed supernumerary atrial signal is small in size and very precocious relative to the ventricular pacing. To avoid this crosstalk, 4 solutions can be envisioned:

  1. reducing the amplitude of ventricular pacing and/or programming ventricular pacing in bipolar mode; these changes did not solve the problem in this patient; in fact, ventricular pacing was already set in bipolar mode; moreover, in the majority of cases, it is more ventricular depolarization (not influenced by pacing amplitude) than the ventricular pacing stimulus which is sensed by the atrial channel;
  2. programming atrial sensing to bipolar mode which was also already the case;
  3. reducing the programmed atrial sensitivity; the programming of a sensitivity at 0.5 mV (0.3 mV initially) allowed resolving the problem of oversensing; this modification of programming, however, would limit the sensing capability of an atrial fibrillation which is often associated with a dampening of the amplitude of the atrial signals;
  4. changing the PVAB methodology; scheduling a long-term absolute blanking may solve the problem but exposes the patient to the risk of undersensing of atrial arrhythmia and particularly of an atrial flutter (risk of 2:1 flutter); in this patient, the programming of partial blanking + solved the problem, the pacemaker temporarily becoming less sensitive at the atrial channel following ventricular pacing.
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